CD163 C-epitope Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD163 C-epitope |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, monkey |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | 0.55-0.75 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of I |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 887-905 on human CD163 protein. Expression: Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the p |
| Other Names | [CD163 antigen; CD163 molecule; Hemoglobin Scavenger Receptor; Macrophage associated antigen; MM130; Scavenger receptor cysteine rich type 1 protein M130; sCD163; Soluble CD163], [CD163; CD163; M130; MM130; SCARI1] |
| Gene, Accession # | [CD163], Gene ID: 9332, NCBI: EAW88662.1, UniProt: D3DUU0 |
| Catalog # | MBS540774 |
| Price | $390 |
| Order / More Info | CD163 C-epitope Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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