FAAH Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFAAH
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionEndogenous cannabinoids have been implicated in addictive behaviors and drug abuse (1). Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid (2). This hydrolase also converts the cannabinoid anandamide, the endogenous ligand for the CB1 cannabinoid receptor, to arachidonic acid, suggesting a role in fatty-acid amide inactivation (2). Mice lacking FAAH1 have significantly higher levels of anandamide in the brain and show decreased sensitivity to pain, further indicating a role for FAAH1 in the regulation of endocannabinoid signaling in vivo (3). FAAH1 null mice also demonstrate an increased preference for alcohol and an increased voluntary uptake of alcohol as compared to wild-type mi
ImmunogenImmunogen: Recombinant protein of human FAAH Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[FAAH; FAAH1; MGC102823; MGC138146]
Gene, Accession #[FAAH], Gene ID: 2166, NCBI: NP_001432.2, UniProt: O00519
Catalog #MBS8503232
Price$310
Order / More InfoFAAH Antibody from MYBIOSOURCE INC.
Product Specific References1. Blednov, Y.A. et al. (2007) Neuropsychopharmacology 32, 1570-82. 2. Cravatt, B.F. et al. (1996) Nature 384, 83-7. 3. Cravatt, B.F. et al. (2001) ProcNatlAcadSci USA 98, 9371-6.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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