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Antigenic Specificity | Mouse FLIP (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1.FLIP exists in 2 forms, FLIPs (short) and FLIPL (long). This item recognises only FLIPL. MBS221590 recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein). FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1. FLIP exists in 2 forms, FLIPs (short) and FLIPL (long). MBS221590 recognises only FLIPL. |
Immunogen | Immunogen: Synthetic peptide from C-terminus of murine FLIPL Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to murine FLIP were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography. Target Species: Mouse |
Other Names | [CASP8 and FADD-like apoptosis regulator isoform 1; CASP8 and FADD-like apoptosis regulator; CASP8 and FADD-like apoptosis regulator; FADD-like antiapoptotic molecule 1; MACH-related inducer of toxicity; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; cellular FLICE-like inhibitory protein; inhibitor of FLICE; usurpin; CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; UsurpinCleaved into the following 2 chains:CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12], [Cflar; Cflar; Cash; Flip; MRIT; CLARP; FLAME; Casper; Gm9845; c-Flip; FLAME-1; I-FLICE; 2310024N18Rik; A430105C05Rik; ENSMUSG00000072980; Cash; CASH; Casper; CLARP; c-FLIP; FLAME-1; I-FLICE; MRIT] |
Gene, Accession # | [FLIP], Gene ID: 12633, NCBI: NP_001276633.1, UniProt: O35732 |
Catalog # | MBS221590 |
Price | $375 |
Order / More Info | Mouse FLIP (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |