LAYN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLAYN
Clone[AT20G8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b,k
FormatProtein A purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionLayilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layili
ImmunogenImmunogen: Recombinant human LAYN (22-235aa) purified from E. coli
Other Names[Layilin isoform 1; Layilin], [LAYN; LAYN]
Gene, Accession #[LAYN], Gene ID: 143903, NCBI: NP_001245319, UniProt: Q6UX15
Catalog #MBS200287
Price$240, $315
Order / More InfoLAYN Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBono P., et al. (2005) Exp Cell Res 1;308 (1): 177-87; Mark L., et al. (1998) The Journal of Cell Biology 143 (2): 429;
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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