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Antigenic Specificity | Phospho-Syntaxin 1A (Ser14) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Syntaxin 1A (Ser14) antibody detects endogenous levels of Syntaxin 1A only when phosphorylated at Serine 14. Description: STX1A is a type IV membrane protein involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. Three splice variant isoforms have been described.Function: Plays a role in hormone and neurotransmitter exocytosis (By similarity). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.Subunit Structure: Interacts (via C-terminus) with KCNB1 (via C-terminus); the inter |
Immunogen | Immunogen: A synthesized peptide derived from human Syntaxin 1A around the phosphorylation site of Serine 14 Subcellular Location: Secreted and Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Cell Junction > Synapse > Synaptosome. Tissue Specificity: Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. Predicted Cross |
Other Names | [HPC 1; Neuron specific antigen HPC1; Neuron-specific antigen HPC-1; OTTHUMP00000174615; OTTHUMP00000174616; OTTHUMP00000174617; OTTHUMP00000174618; P35-1; STX1; STX1A; STX1A_HUMAN; SYN1A; Syntaxin 1A (brain); Syntaxin 1A brain; Syntaxin-1A] |
Gene, Accession # | [STX1A], Gene ID: 6804, NCBI: NP_001159375.1, UniProt: Q16623 |
Catalog # | MBS9601232 |
Price | $240, $280 |
Order / More Info | Phospho-Syntaxin 1A (Ser14) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |