Phospho-Syntaxin 1A (Ser14) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Syntaxin 1A (Ser14)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-Syntaxin 1A (Ser14) antibody detects endogenous levels of Syntaxin 1A only when phosphorylated at Serine 14. Description: STX1A is a type IV membrane protein involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. Three splice variant isoforms have been described.Function: Plays a role in hormone and neurotransmitter exocytosis (By similarity). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.Subunit Structure: Interacts (via C-terminus) with KCNB1 (via C-terminus); the inter
ImmunogenImmunogen: A synthesized peptide derived from human Syntaxin 1A around the phosphorylation site of Serine 14 Subcellular Location: Secreted and Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Cell Junction > Synapse > Synaptosome. Tissue Specificity: Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. Predicted Cross
Other Names[HPC 1; Neuron specific antigen HPC1; Neuron-specific antigen HPC-1; OTTHUMP00000174615; OTTHUMP00000174616; OTTHUMP00000174617; OTTHUMP00000174618; P35-1; STX1; STX1A; STX1A_HUMAN; SYN1A; Syntaxin 1A (brain); Syntaxin 1A brain; Syntaxin-1A]
Gene, Accession #[STX1A], Gene ID: 6804, NCBI: NP_001159375.1, UniProt: Q16623
Catalog #MBS9601232
Price$240, $280
Order / More InfoPhospho-Syntaxin 1A (Ser14) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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