Mouse CD49d/VLA-4a Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Mouse CD49d/VLA-4a antibody, protein, ELISA kits.
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| Antigenic Specificity | Mouse CD49d/VLA-4a |
| Clone | [PS/2] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2b kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD49d, the alpha 4 chain (100 kDa) of the VLA-4 integrin heterodimer (Mr 150-kDa). VLA-4 belongs to the beta 1-integrin family, which functions both as cell-matrix and cell-cell receptors.^1-3 As a matrix receptor VLA-4 binds to an alternatively spliced domain of fibronectin, while as a cellular receptor it associates with its counter-receptor ligand VCAM-1. ^1, 2 In addition to CD44/pgp-1, VLA-4 has been shown to be important for lymphopoiesis, and is also believed to be important for extravasation of lymphocytes into sites of inflammation as a second signal in addition to LFA/ICAM-1. ^2, 3 CD49d/VLA-4 is expressed in low amounts on resting lymphocytes and monocytes, is absent or minimally detectable on stromal cells, whereas |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS673115 |
| Price | $260 |
| Order / More Info | Mouse CD49d/VLA-4a Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Miyake, K., I. L. Weissman, J. S. Greenberger, and P. W. Kincade. 1991. J. Exp. Med. 173:599.2. Christensen, J. P., E. C. Andersson, A. Scheynius, O. Marker, and A. R. Thomsen. 1995. J. Immunol. 154:5293.3. Henseleit, U., K. Steinbrink, C. Sunderkotter, M. Goebeler, J. Roth, and C. Sorg. 1994. Exp. Dermatol. 3:2494. Lauri, D., C. De Giovanni, T. Biondelli, E. Lalli, L. Landuzzi, A. Facchini, G. Nicoletti, P. Nanni, E. Dejana, and P. L. Lollini. 1993. Br. J. Cancer 68:862. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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