LMTK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLMTK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: LMTK3 antibody detects endogenous levels of total LMTK3. Function: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).Subunit Structure: Interacts with ESR1 (PubMed:21602804). Interacts with AP-2 complex subunit alpha (By similarity).Similarity: Belongs to the protein kinase superfamily. Tyr protein
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Predicted Cross Reactivity: Pig, Bovine Similarity: Pig (100%), Bovine (100%)
Other Names[BC059845; KIAA1883; Lemur tyrosine kinase 3; LMR3; MGC90743; Serine/threonine-protein kinase LMTK3; TYKLM3]
Gene, Accession #[LMTK3], Gene ID: 114783, NCBI: Q96Q04.2, UniProt: Q96Q04
Catalog #MBS9604865
Price$240, $280
Order / More InfoLMTK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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