BRCA1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BRCA1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 100ug/100ul |
| Applications | Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human BRCA1. BRCA1 is a nuclear phosphoprotein that plays a role in maintaining genomic stability. As a tumor suppressor, BRCA1 combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). BRCA1 associates with RNA polymerase II through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Other diseases associated with BRCA1 i |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the human BRCA1 Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide |
| Other Names | [BRCA1; Breast cancer type 1 susceptibility protein; breast cancer type 1 susceptibility protein; BRCA1, DNA repair associated; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1Curated] |
| Gene, Accession # | [BRCA1], Gene ID: 672, NCBI: AAC37594.1 |
| Catalog # | MBS4152801 |
| Price | $260 |
| Order / More Info | BRCA1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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