APC/Adenomatous Polyposis Coli/FAP (Tumor Suppressor) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-APC/Adenomatous Polyposis Coli/FAP (Tumor Suppressor) antibody, protein, ELISA kits.
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| Antigenic Specificity | APC/Adenomatous Polyposis Coli/FAP (Tumor Suppressor) |
| Clone | [ALi 12-28] |
| Host Species | Mouse |
| Reactive Species | humandoes not react with mouse. |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2,843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. Functions as a tumor suppressor, promoting rapid degradation of CTNNB1 and is a negative regulator of Wnt signaling. Also plays a role in HGF-induced cell migration. Required for MMP9 up-regulation via the JNK si |
| Immunogen | Immunogen: Recombinant fragment of human APC protein (around aa 1-433) |
| Other Names | [Adenomatous Polyposis Coli; CC1; Deleted in polyposis 2.5 (DP2.5); DP2; DP3; FAP; FPC; GS; Protein APC] |
| Gene, Accession # | [APC], Gene ID: 324, NCBI: NP_000029.2, UniProt: P25054 |
| Catalog # | MBS4380984 |
| Price | $190, $340, $340 |
| Order / More Info | APC/Adenomatous Polyposis Coli/FAP (Tumor Suppressor) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sunkel, C.E. and Glover, D.M. 1988. J. Cell Sci. 89: 25-38. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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