NDFIP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNDFIP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total NDFIP1 protein. Activates HECT domain-containing E3 ubiquitin-protein ligases, including NEDD4 and ITCH, and consequently modulates the stability of their targets. As a result, controls many cellular processes. Prevents chronic T-helper cells-mediated inflammation by activating ITCH and thus controlling JUNB degradation By similarity. In cortical neurons, mediates the ubiquitination of SLC11A2/DMT1 by NEDD4L, leading to down-regulation of the divalent metal transporter and protection of the cells from cobalt and iron toxicity. Modulates EGFR signaling through multiple pathways. In particular, may regulate the ratio of AKT1-to-MAPK8 signaling in response to EGF, acting on AKT1 probably through
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human NDFIP1.
Other Names[Breast cancer-associated protein SGA-1M; MGC10924; N4WBP5; NDFIP1; Nedd4 family interacting protein 1]
Gene, Accession #[NDFIP1], Gene ID: 80762, NCBI: NP_085048.1, UniProt: Q9BT67
Catalog #MBS9413102
Price$200, $255
Order / More InfoNDFIP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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