KDEL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKDEL
Clone[1F2]
Host SpeciesMouse
Reactive Specieshuman; mouse; rat
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionDetects KDEL tagged proteins. The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER.
ImmunogenImmunogen: KDEL peptide (C-AVKDEL-COOH) conjugated at the N-terminal to Bovine Serum Albumin (BSA). Conjugate: Unconjugated. Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Other Namesn/a
Gene, Accession #[KDEL]
Catalog #MBS809060
Price$390
Order / More InfoKDEL Antibody from MYBIOSOURCE INC.
Product Specific References1. Ozawa K., et al. (2008) Mol Pharmacol. 74:1610. 2. Austin R.C., et al. (2003) J Biol Chem. 278: 17438.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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