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Antigenic Specificity | CLK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CLK4 protein. Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.Schultz J., Genomics 71:368-370(2001).McNally T., Protein Sci. 12:1562-1566(2003).Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human CLK4. |
Other Names | [Dual specificity protein kinase CLK4; EC 2.7.12.1; CDC-like kinase 4; CLK4] |
Gene, Accession # | [CLK4], Gene ID: 57396, NCBI: NP_065717.1, UniProt: Q9HAZ1 |
Catalog # | MBS9406581 |
Price | $200, $255 |
Order / More Info | CLK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |