ROS1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityROS1
Clonepolyclonal
Host SpeciesRabbit
Reactive SpeciesArabidopsis thaliana
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionBifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed: 25240767). Generates 3'-phosphor-alpha, beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate (PubMed: 25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation mod
ImmunogenImmunogen: Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)
Other Names[Protein ROS1; DEMETER-like protein 1; Repressor of silencing 1; ROS1; DML1; At2g36490; F1O11.12]
Gene, Accession #[ROS1], Gene ID: 818224, NCBI: NP_181190.3, UniProt: Q9SJQ6
Catalog #MBS7051265
Price$160, $235
Order / More InfoROS1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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