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Antigenic Specificity | FASN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Fatty acid synthase (FASN) catalyzes the synthesis of long-chain fatty acids from acetyl-CoA and malonyl-CoA. FASN is active as a homodimer with seven different catalytic activities and produces lipids in the liver for export to metabolically active tissues or storage in adipose tissue. In most other human tissues, FASN is minimally expressed since they rely on circulating fatty acids for new structural lipid synthesis (1).Recently, increased expression of FASN has emerged as a phenotype common to most human carcinomas. In breast cancer, immunohistochemical staining showed that the levels of FASN are directly related to the size of breast tumors (2). Studies also showed that FASN is highly expressed in lung and prostate cancers and that FAS |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [FASN; FAS; MGC14367; MGC15706; OA-519; SDR27X1], [FASN; FASN; FAS; OA-519; SDR27X1; FAS] |
Gene, Accession # | [FASN], Gene ID: 2194, NCBI: P49327.3, UniProt: P49327 |
Catalog # | MBS125054 |
Price | $200, $275, $430 |
Order / More Info | FASN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |