Phospho-Ser62,67 Synapsin I Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-Ser62,67 Synapsin I
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: Specific for ~78k synapsin I doublet phosphorylated at Ser62,67. Immunolabeling of the synapsin I band is blocked by preadsorption with the phospho-peptide used as antigen but not be the corresponding dephospho-peptide. Affinity purified rabbit polyclonal antibody
ImmunogenAntigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser62,67 of synapsin I. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser62/67 conjugated to KLH. Immunogen Species: Rat
Other Names[synapsin-1; Synapsin-1; synapsin-1; Synapsin I], [SYN1; SYN1]
Gene, Accession #[SYN1], Gene ID: 281510, NCBI: NP_776616.1, UniProt: P17599
Catalog #MBS502116
Price$360
Order / More InfoPhospho-Ser62,67 Synapsin I Antibody from MYBIOSOURCE INC.
Product Specific References• Jovanovic JN, Benfenati, F, Siow YL, Sihra TS, Sanghera JS, Pelech SL, Greengard P,Czernik AJ (1996) Neurotrophins stimulate phosphorylation of Synapsin I by MAP kinase and regulate Synapsin I-actin interactions. Neurobiology 93:3679-3683.• Czernik AJ, Pang DT, Greengard P (1987) Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I. Proc Natl Acad Sci (USA) 84:7518-7522.• Feng J, Chi P, Blanpied TA, Xu YM, Magarinos AM, Ferreira A, Takahashi RH, Kao HT, McEwen BS, Ryan TA, Augustine GJ, Greengard P (2002) Regulation of neurotransmitter release by synapsin III. J Neurosci 22:4372-4380.• Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Jr., Greengard P, Czernik AJ (2001) Opposing changes in phosphorylation of specific sites in synapsin I during Ca2 -dependent glutamate release in isolated nerve terminals. J Neurosci 21:7944-7953.• Kao HT, Song HJ, Porton B, Ming GL, Hoh J, Abraham M, Czernik AJ, Pieribone VA, Poo MM, Greengard P (2002) A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth. Nature Neurosci 5:431-437.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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