IFI-56K Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIFI-56K
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: IFI-56K antibody detects endogenous levels of total IFI-56K. Function: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for thei
ImmunogenImmunogen: A synthesized peptide derived from human IFI-56K Tissue Specificity: By type I interferons, dsRNAs and viruses. Predicted Cross Reactivity: Horse Similarity: Horse (86%)
Other Names[C56; G10P1; GARG 16; GARG16; IFI 56; IFI 56K; IFI-56K; IFI56; IFIT-1; Ifit1; IFIT1_HUMAN; IFNAI1; Interferon alpha inducible protein (MW 56kD); Interferon induced 56 kDa protein; Interferon induced protein 56; Interferon inducible mRNA 561; Interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1; ISG56; OTTHUMP00000020062; P56; RNM561]
Gene, Accession #[IFI-56K], Gene ID: 3434, NCBI: NP_001257857.1, UniProt: P09914
Catalog #MBS9602136
Price$240, $280
Order / More InfoIFI-56K Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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