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Antigenic Specificity | IFI-56K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IFI-56K antibody detects endogenous levels of total IFI-56K. Function: Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for thei |
Immunogen | Immunogen: A synthesized peptide derived from human IFI-56K Tissue Specificity: By type I interferons, dsRNAs and viruses. Predicted Cross Reactivity: Horse Similarity: Horse (86%) |
Other Names | [C56; G10P1; GARG 16; GARG16; IFI 56; IFI 56K; IFI-56K; IFI56; IFIT-1; Ifit1; IFIT1_HUMAN; IFNAI1; Interferon alpha inducible protein (MW 56kD); Interferon induced 56 kDa protein; Interferon induced protein 56; Interferon inducible mRNA 561; Interferon-induced 56 kDa protein; Interferon-induced protein with tetratricopeptide repeats 1; ISG56; OTTHUMP00000020062; P56; RNM561] |
Gene, Accession # | [IFI-56K], Gene ID: 3434, NCBI: NP_001257857.1, UniProt: P09914 |
Catalog # | MBS9602136 |
Price | $240, $280 |
Order / More Info | IFI-56K Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |