BRSK1 (C-term), 654-684 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BRSK1 (C-term), 654-684 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.25 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This BRSK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 654-684 amino acids from the C-terminal region of human BRSK1. BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regu |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase BRSK1; Brain-selective kinase 1; Brain-specific serine/threonine-protein kinase 1; BR serine/threonine-protein kinase 1; Serine/threonine-protein kinase SAD-B; Synapses of Amphids Defective homolog 1; SAD1 homolog; hSAD1; BRSK1; KIAA1811; SAD1; SADB] |
| Gene, Accession # | [BRSK1], Gene ID: 84446, NCBI: NP_115806.1, UniProt: Q8TDC3 |
| Catalog # | MBS9202562 |
| Price | $165, $370 |
| Order / More Info | BRSK1 (C-term), 654-684 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lu, R., et al., J. Biol. Chem. 279(30):31164-31170 (2004). Lizcano, J.M., et al., EMBO J. 23(4):833-843 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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