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Antigenic Specificity | CD40L Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD40 ligand(CD40L) is a type II membrane protein of 261 amino acids on activated T cells that induces B cell proliferation and immunoglobulin secretion. It has homology with tumour necrosis factor-alpha and -beta, and has important functions in B-cell activation and differentiation. Human CD40L with 5 exons, is mapped to the proximal region of the mouse X chromosome on Xq26.3-27.1, and can be detected on T cells but is absent from B cells and monocytes. Since CD40L is expressed on platelets and released from them on activation, its predictive value as a marker for clinical outcome and the therapeutic effect of inhibition of glycoprotein IIb /IIIa receptor in patients with acute coronary syndromes was investigated. The soluble C |
Immunogen | Immunogen: E Coli-derived human CD40L recombinant protein (Position: E108-L261). Subcellular Localization: Cell membrane. Tissue Specificity: Specifically expressed on activated CD4 T- lymphocytes. |
Other Names | [CD40 ligand; CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; CD40LG; CD40L; TNFSF5; TRAP] |
Gene, Accession # | [CD40L], Gene ID: 959, NCBI: NP_000065.1, UniProt: P29965 |
Catalog # | MBS1750573 |
Price | $280 |
Order / More Info | CD40L Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |