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Antigenic Specificity | SH2B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SH2B1 antibody detects endogenous levels of total SH2B1. Description: This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.Function: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic |
Immunogen | Immunogen: A synthesized peptide derived from human SH2B1 Subcellular Location: Cytoplasm. Membrane. Nucleus. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Widely expressed with highest levels in skeletal muscle and ovary. Predicted Cross Reactivity: Horse, Sheep, Dog Similarity: Horse (100%), Sheep (92%), Dog (100%) |
Other Names | [DKFZp547G1110; FLJ30542; KIAA1299; PH and SH2 domain-containing signaling mediator; Pro-rich; Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 B; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; SH2-B signaling protein; SH2B; SH2B adapter protein 1; SH2B adaptor protein 1; Sh2b1; SH2B1 protein; SH2B1_HUMAN] |
Gene, Accession # | [SH2B1], Gene ID: 25970, NCBI: NP_001139267.1, UniProt: Q9NRF2 |
Catalog # | MBS9608041 |
Price | $240, $280 |
Order / More Info | SH2B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |