SH2B1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySH2B1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: SH2B1 antibody detects endogenous levels of total SH2B1. Description: This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described.Function: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways mediated by Janus kinase (JAK) and receptor tyrosine kinases, including the receptors of insulin (INS), insulin-like growth factor I (IGF1), nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic
ImmunogenImmunogen: A synthesized peptide derived from human SH2B1 Subcellular Location: Cytoplasm. Membrane. Nucleus. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Widely expressed with highest levels in skeletal muscle and ovary. Predicted Cross Reactivity: Horse, Sheep, Dog Similarity: Horse (100%), Sheep (92%), Dog (100%)
Other Names[DKFZp547G1110; FLJ30542; KIAA1299; PH and SH2 domain-containing signaling mediator; Pro-rich; Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 B; SH2 domain-containing protein 1B; SH2 domain-containing putative adapter SH2-B; SH2-B signaling protein; SH2B; SH2B adapter protein 1; SH2B adaptor protein 1; Sh2b1; SH2B1 protein; SH2B1_HUMAN]
Gene, Accession #[SH2B1], Gene ID: 25970, NCBI: NP_001139267.1, UniProt: Q9NRF2
Catalog #MBS9608041
Price$240, $280
Order / More InfoSH2B1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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