GCK - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGCK - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human GCK
Other Names[glucokinase isoform 1; Glucokinase; glucokinase; glucokinase; Hexokinase type IV; HK IV; Hexokinase-4; HK4; Hexokinase-D]
Gene, Accession #[GCK], Gene ID: 2645, NCBI: NP_000153.1, UniProt: P35557
Catalog #MBS3224221
Price$335
Order / More InfoGCK - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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