KDM4D Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKDM4D
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.2 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total KDM4D protein. JMJD2D (Jumonji domain-containing protein 2D), also known as JHDM3D or KDM4D, is a 520 amino acid protein that belongs to the JHDM3 histone demethylase family. Localized to the nucleus, JMJD2D functions as a histone demethylase that removes specific methyl residues from Histone H3, thereby playing a crucial role in the histone code. JMJD2D binds iron as a cofactor and contains one JMJC domain and one JMJN domain, both of which are thought to exhibit enzymatic activity during chromatin remodeling events. In addition, JMJD2D forms a complex with the ligand-bound form of the androgen receptor (AR) and, through this interaction, activates AR expression. Overexpression of AR is assoc
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to a region derived from internal residues of human lysine (K)-specific demethylase 4D
Other Names[JMJD2D]
Gene, Accession #[KDM4D], Gene ID: 55693, NCBI: NP_060509.2, UniProt: Q6B0I6
Catalog #MBS9400781
Price$255
Order / More InfoKDM4D Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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