Human Interleukin-2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human Interleukin-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IL-2 is a T cell stimulatory cytokine best known for inducing T cell proliferation and NK cell proliferation and activation (1, 2). IL-2 also promotes peripheral development of Treg cells (4, 5). Conversely, IL-2 is involved in activation induced cell death (AICD) that is observed post T cell expansion by increasing levels of Fas on CD4+ T cells (3). The effects of IL-2 are mediated through a trimeric receptor complex consisting of IL-2Ralpha, IL-2Rbeta and the common gamma chain, gamma c (1, 2). IL-2 Ralpha binds exclusively to IL-2 with low affinity and increases binding affinity of the whole receptor complex including IL-2Rbeta and gamma c subunits. IL-2Rbeta is also used by IL-15 (1, 2). The common gamma c is used by other cytokines inc |
| Immunogen | Immunogen: Recombinant protein of human IL2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [IL2; TCGF; lymphokine] |
| Gene, Accession # | [IL-2], Gene ID: 3558, NCBI: NP_000577.2, UniProt: P60568 |
| Catalog # | MBS8503236 |
| Price | $310 |
| Order / More Info | Human Interleukin-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Ma, A. et al. (2006) Annu Rev Immunol 24, 657-79. 2. Gaffen, S.L. and Liu, K.D. (2004) Cytokine 28, 109-23. 3. Jaleco, S. et al. (2003) J Immunol 171, 61-8. 4. Fehervari, Z. et al. (2006) Trends Immunol 27, 109-11. 5. Antony, P.A. et al. (2006) J Immunol 176, 5255-66. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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