Edit |   |
---|---|
Antigenic Specificity | CYBA (C-term), 117-145 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA. Cytochrome b is comprised of a light chain (alpha) and aheavy chain (beta). This gene encodes the light, alpha subunitwhich has been proposed as a primary component of the microbicidaloxidase system of phagocytes. Mutations in this gene are associatedwith autosomal recessive chronic granulomatous disease (CGD), thatis characterized by the failure of activated phagocytes to generatesuperoxide, which is important for the microbicidal activity ofthese cells. |
Immunogen | n/a |
Other Names | [Cytochrome b-245 light chain; Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox; CYBA] |
Gene, Accession # | [CYBA], Gene ID: 1535, NCBI: NP_000092.2, UniProt: P13498 |
Catalog # | MBS9214682 |
Price | $165, $370 |
Order / More Info | CYBA (C-term), 117-145 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Katakami, N., et al. Atherosclerosis 212(2):534-538(2010) Tu, Y.C., et al. Acta Pharmacol. Sin. 31(7):874-880(2010) Moreno, M.U., et al. Drug News Perspect. 23(5):316-324(2010) Cross, D.S., et al. BMC Genet. 11, 51 (2010) : |