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Antigenic Specificity | CKMT1A/CKMT1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 3 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CKMT1A/CKMT1B protein. Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiqu |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human Creatine kinase, mitochondrial 1B |
Other Names | [CKMT; CKMT1; UMTCK] |
Gene, Accession # | [CKMT1A/CKMT1B], Gene ID: 548596, NCBI: NP_001015001.1, UniProt: P12532 |
Catalog # | MBS9404635 |
Price | $255 |
Order / More Info | CKMT1A/CKMT1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |