Human FAS ligand (FasL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human FAS ligand (FasL) |
| Clone | [GM-5F4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS)and CELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human Fas ligand (FasL). Background: The FAS ligand (FASL, CD95), a member of the tumor necrosis factor family, induces apoptosis in FAS-bearing cells (1). FASL is a type II membrane receptor with a soluble form that can be released into the extracellular fluid by proteolytic processing. Various cells express Fas, whereas FASL is expressed in activated splenocytes and thymocytes (2). In the immune system, Fas and FasL are involved in down-regulation of immune reactions as well as in T cellmediated cytotoxicity. Malfunction of the Fas system causes lymphoproliferative disorders and accelerates autoimmune diseases, whereas its exacerbation may cause tissue destruction. |
| Immunogen | Immunogen: Immunogen: cDNA |
| Other Names | [CD95; Fas ligand], [FASLG; FASLG; APTL; FASL; CD178; CD95L; ALPS1B; CD95-L; TNFSF6; APT1LG1; APT1LG1; CD95L; FASL; TNFSF6; APTL; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA] |
| Gene, Accession # | Gene ID: 356, NCBI: NP_000630.1, UniProt: P48023 |
| Catalog # | MBS468025 |
| Price | $505 |
| Order / More Info | Human FAS ligand (FasL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nagata S (1996). Apoptosis mediated by the Fas system. Prog Mol Subcell Biol 16:87-103Suda T,Hashimoto H, Tanaka M, Ochi T, Nagata S (1997). Membrane Fas ligand kills humanperipheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med186(12):2045-50Nagata S and Golstein P (1995). The Fas death factor. Science 10;267(5203):1449-56 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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