Edit |   |
---|---|
Antigenic Specificity | Hsp90 |
Clone | [4F3.E8] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA; Immunoprecipitation; Immunohistochemistry; Immunocytochemistry; Immunoblotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Hsp90. This antibody recognizes human, mouse, and rat Hsp90alpha and beta. Other species have not been tested. Hsp90 is an abundantly and ubiquitously expressed heat shock protein found in all eukaryotic cells. It exists in two principal forms, alpha and beta, which share 85% sequence homology. Both forms are expressed in the cytosol. Hsp90alpha exists primarily as a homodimer while Hsp90beta exists mainly as a monomer. Hsp90 plays a role in folding, assembly, maturation, and stabilization of specific proteins as a key component of a chaperone complex. Most of the Hsp90-regulated proteins that have been identified are involved in cell signaling; kinases, v-Src, Wee1, c-Raf, and p53 are some examples. When bound to ATP, Hsp90 in |
Immunogen | Antigen: Recombinant human Hsp90 prufified from E.coli. Preservative: None. |
Other Names | n/a |
Gene, Accession # | [Hsp90] |
Catalog # | MBS190558 |
Price | $335 |
Order / More Info | Hsp90 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |