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Antigenic Specificity | ERO1LB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EROILB is an essential oxidoreductase that oxidizes proteins In the endoplasmic reticulum to produce disulfide bonds. It acts by oxidizing directly P4HBIPDI isomerase through a direct disulfide exchange. It does not act as a direct oxidant of folding substrate, but relies on P4HBIPDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDr and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Glutathione may be required to regulate its activity in the endoplasmic reticulum. It may be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source |
Immunogen | Immunogen: Fusion of ERO1LB Calculated Molecular Weight: 54kd Observed Molecular Weight: 54kd |
Other Names | [ERO1-like protein beta; ERO1-like protein beta; ERO1-like protein beta; ERO1-L-beta; endoplasmic oxidoreductin-1-like protein B; endoplasmic reticulum oxidoreductin-1-like protein B; oxidoreductin-1-L-beta; ERO1-like beta (S. cerevisiae); Endoplasmic reticulum oxidoreductin-1-like protein B; Oxidoreductin-1-L-beta] |
Gene, Accession # | [ERO1LB], Gene ID: 56605, NCBI: Q86YB8.2 |
Catalog # | MBS2525608 |
Price | $195, $270, $435 |
Order / More Info | ERO1LB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |