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Antigenic Specificity | Caspase-3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, sheep, dog, porcine, monkey, bovine, chicken, guinea pig, hamster, rabbit, Xenopus |
Isotype | n/a |
Format | unconjugated |
Size | 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus Caspase-3. Detects a band of ~36kDa by Western blot. The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which c |
Immunogen | Immunogen: Synthetic peptide corresponding to a portion of human caspase-3. The sequence differs from rat caspase-3 by 1 aa and from mouse by 2 aa. |
Other Names | [Caspase-3, pAb], [CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1] |
Gene, Accession # | Gene ID: 836, NCBI: P42574.2, UniProt: P42574 |
Catalog # | MBS565717 |
Price | $435 |
Order / More Info | Caspase-3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |