Phospho-P21CIP1 (T145) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-P21CIP1 (T145)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), Dot Blot (DB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis P21CIP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T145 of human P21CIP1. P21CIP1 is a potent cyclin-dependent kinase inhibitor. This protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. Expression is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. P21CIP1 can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage
Immunogenn/a
Other Names[Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1]
Gene, Accession #[CDKN1A], Gene ID: 1026, NCBI: NP_000380.1, UniProt: P38936
Catalog #MBS9203875
Price$165, $370
Order / More InfoPhospho-P21CIP1 (T145) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesScott, S.A., et al., Leuk. Res. 28(12):1293-1301 (2004). Amini, S., et al., J. Biol. Chem. 279(44):46046-46056 (2004). Chen, T., et al., Cancer Res. 64(20):7412-7419 (2004). Sieburg, M., et al., J. Virol. 78(19):10399-10409 (2004). Giraud, S., et al., Oncogene 23(44):7391-7398 (2004).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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