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Antigenic Specificity | FUS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FUS antibody detects endogenous levels of total FUS. Function: Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.Subunit Structure: Component of nuclear riboprotein complexes. Interacts with ILF3, TDRD3 and SF1. Interacts through its C-terminus with SFRS13A. Interacts with OTUB1 and SARNP.Interacts with LRSAM1 (PubMed:27615052).Post-translational Modifications: Arg-216 and Arg-218 are dimethylated, probably to asymmetric dimethylarginine.Similarity: Belongs to the RRM TET family. |
Immunogen | Immunogen: A synthesized peptide derived from human FUS Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Rabbit (92%), Dog (100%), Chicken (100%), Xenopus (100%) |
Other Names | [75 kDa DNA pairing protein; 75 kDa DNA-pairing protein; ALS6; Amyotrophic lateral sclerosis 6; fus; FUS CHOP; Fus like protein; FUS_HUMAN; FUS1; Fused in sarcoma; Fusion (involved in t(12; 16) in malignant liposarcoma); Fusion derived from t(12; 16) malignant liposarcoma; Fusion gene in myxoid liposarcoma; Heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; hnRNPP2; Oncogene FUS; Oncogene TLS; POMp75; RNA binding protein FUS; RNA-binding protein FUS; TLS; TLS CHOP; Translocated in liposarcoma; Translocated in liposarcoma protein] |
Gene, Accession # | [FUS], Gene ID: 2521, NCBI: NP_001164105.1, UniProt: P35637 |
Catalog # | MBS9608760 |
Price | $240, $280 |
Order / More Info | FUS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |