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Antigenic Specificity | Phospho-IL-10R alpha (Tyr496) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-IL-10R alpha (Tyr496) antibody detects endogenous levels of IL-10R alpha only when phosphorylated at Tyrosine 496. Description: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines.Function: Receptor for IL10; binds IL10 with a high affinity.Similarity: Belongs to the type II cytokine receptor family. |
Immunogen | Immunogen: A synthesized peptide derived from human IL-10R alpha around the phosphorylation site of Tyrosine 496 Subcellular Location: Membrane. Tissue Specificity: Spleen, thymus, and PBMC. Weak expression in pancreas, skeletal muscle, brain, heart, and kidney. Placenta, lung, and liver showed intermediate levels. Monocytes, B-cells, large granular lymphocytes, and T-cells express high levels. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Horse (89%), Rabb |
Other Names | [CD210; CDw210a; CDw210a antigen; HIL 10R; HIL10R; I10R1_HUMAN; IL 10R 1; IL 10R A; IL 10R; IL 10R1; IL-10 receptor subunit alpha; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10RA; IL10R; IL10R1; IL10RA; Interleukin 10 receptor alpha; Interleukin 10 receptor alpha chain; Interleukin-10 receptor subunit 1; Interleukin-10 receptor subunit alpha] |
Gene, Accession # | [IL10RA], Gene ID: 3587, NCBI: NP_001549.2, UniProt: Q13651 |
Catalog # | MBS9601204 |
Price | $240, $280 |
Order / More Info | Phospho-IL-10R alpha (Tyr496) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |