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Antigenic Specificity | Human ALK2 (Activin R1A) |
Clone | [9J17] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was selected for its ability to detect human ALK2. Activin RIA, also known as ALK2, TSK7L, SKR1, TSRI, and ACTRI, is a glycosylated 65 kDa type I receptor in the TGFbeta serine/threonine kinase receptor family. Binding of TGFbeta superfamily ligands induces formation of a heterotetrameric complex that contains two chains each of a type I and a type II receptor in multiple combinations. The type II receptors phosphorylate the type I receptors which then phosphorylate and activate Smad signal transduction proteins. Activin RIA functions in a wide variety of growth and differentiation processes including gastrulation, skeletal system development, and cardiac morphogenesis. Mature human Activin RIA consists of a 103 aa extracellul |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human ALK2 extra cellular domain. IgG1 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. Antigen: Recombinant human ALKD2 extracellular domain. |
Other Names | [ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2], [ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2] |
Gene, Accession # | [ALK2 (Activin R1A)], Gene ID: 90, NCBI: NP_001096.1, UniProt: Q074771 |
Catalog # | MBS690711 |
Price | $490 |
Order / More Info | Human ALK2 (Activin R1A) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |