Human ALK2 (Activin R1A) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ALK2 (Activin R1A)
Clone[9J17]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis antibody was selected for its ability to detect human ALK2. Activin RIA, also known as ALK2, TSK7L, SKR1, TSRI, and ACTRI, is a glycosylated 65 kDa type I receptor in the TGFbeta serine/threonine kinase receptor family. Binding of TGFbeta superfamily ligands induces formation of a heterotetrameric complex that contains two chains each of a type I and a type II receptor in multiple combinations. The type II receptors phosphorylate the type I receptors which then phosphorylate and activate Smad signal transduction proteins. Activin RIA functions in a wide variety of growth and differentiation processes including gastrulation, skeletal system development, and cardiac morphogenesis. Mature human Activin RIA consists of a 103 aa extracellul
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human ALK2 extra cellular domain. IgG1 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. Antigen: Recombinant human ALKD2 extracellular domain.
Other Names[ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2], [ACVR1; FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2]
Gene, Accession #[ALK2 (Activin R1A)], Gene ID: 90, NCBI: NP_001096.1, UniProt: Q074771
Catalog #MBS690711
Price$490
Order / More InfoHuman ALK2 (Activin R1A) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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