IL-12A Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL-12A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: IL-12A antibody is human specific. IL-12A antibody will not cross-react with IL-12B. IL-12A is subunit of the cytokine IL-12 which acts on T- and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 35-kD subunit and a 40-kD subunit that is a member of the cytokine receptor family (1). IL-12 is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells (1,2). The responses of lymphocytes to IL-12 are mediated by the activator of transcription protein STAT4 (2). Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate im |
| Immunogen | Immunogen: IL-12A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IL-12A. Buffer: Supplied in PBS containing 0.02% sodium azide. Positive Control 1: HeLa Cell Lysate |
| Other Names | [Interleukin 12A; Interleukin 12 alpha; p35; natural killer cell stimulatory factor 1; NKSF1; cytotoxic lymphocyte maturation factor 1; CLMF; NF cell stimulatory factor chain 1; NFSK], [IL12A; IL12A; P35; CLMF; NFSK; NKSF1; IL-12A; NKSF1; IL-12A; CLMF p35; NKSF1] |
| Gene, Accession # | [IL 12A], Gene ID: 3592, NCBI: NP_000873, UniProt: P29459 |
| Catalog # | MBS154392 |
| Price | $375 |
| Order / More Info | IL-12A Antibody from MYBIOSOURCE INC. |
| Product Specific References | Gee K, Guzzo C, Che Mat NF, et al. The IL-12 family of cytokines in infection, inflammation and autoimmune disorders. Inflamm. Allergy Drug Targets 2009; 8:40-52. Sinigaglia F, D'Ambrosio D, Panina-Bordignon P, et al. Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function. Immunol. Rev. 1999; 170:65-72. Bogdan C, Rollinghoff M, and Diefenbach A. The role of nitric oxide in innate immunity. Immunol. Rev. 2000; 173:17-26. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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