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Antigenic Specificity | NEDD8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neural precursor cell-expressed developmentally downregulated protein 8 (NEDD8), also known as Rub1 (related to ubiquitin 1) in plants and yeast, is a member of the ubiquitin-like protein family (1, 2). The covalent attachment of NEDD8 to target proteins, termed neddylation, is a reversible, multi-step process analogous to ubiquitination. NEDD8 is first synthesized in a precursor form with a carboxy-terminal extension peptide that is removed by either the UCH-L3 or NEDP1/DEN1 hydrolase protein to yield a mature NEDD8 protein (3, 4). Mature NEDD8 is then covalently linked to target proteins via the carboxy-terminal glycine residue in a reaction catalyzed by the APP-BP1/Uba3 heterodimer complex and Ubc12 as the E1- and E2-like enzymes, respec |
Immunogen | Immunogen: Recombinant protein of human NEDD8 Observed Molecular Weight: 9kDa |
Other Names | [NEDD8; FLJ43224; MGC104393; MGC125896; MGC125897; Nedd-8] |
Gene, Accession # | [NEDD8], Gene ID: 4738, NCBI: NP_006147.1 |
Catalog # | MBS2530154 |
Price | $150, $225, $360 |
Order / More Info | NEDD8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |