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Antigenic Specificity | Myoglobin (Muscle Cell Marker) |
Clone | [MB/2105] |
Host Species | Mouse |
Reactive Species | human, mouse, rat. |
Isotype | IgG2b, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions. |
Immunogen | Immunogen: Recombinant human full-length Myoglobin (MB) protein. Positive Control: SK-BR3 or T47D Cells. Skeletal or Cardiac Muscle |
Other Names | [MB; Myoglobin; PVALB] |
Gene, Accession # | [MB], Gene ID: 4151, NCBI: NP_005359.1, UniProt: P02144 |
Catalog # | MBS4380618 |
Price | $190, $340, $340 |
Order / More Info | Myoglobin (Muscle Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Qiu, Y., et al. 1998. Identification of myoglobin in human smooth muscle. J. Biol. Chem. 273: 23426-23432. |