Phospho-FRAP1 (T2446) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Phospho-FRAP1 (T2446) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.45 |
| Applications | Dot Blot (DB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This FRAP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2446 of human FRAP1. FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. |
| Immunogen | n/a |
| Other Names | [Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1; MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1] |
| Gene, Accession # | [MTOR], Gene ID: 2475, NCBI: NP_004949.1, UniProt: P42345 |
| Catalog # | MBS9206421 |
| Price | $165, $370 |
| Order / More Info | Phospho-FRAP1 (T2446) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dowling,R.J., Cancer Res. 67 (22), 10804-10812 (2007) Bai,X., Science 318 (5852), 977-980 (2007) Zhou,J., Proc. Natl. Acad. Sci. U.S.A. 104 (41), 16158-16163 (2007) Radulovic,S., J BUON 12 SUPPL 1, S151-S162 (2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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