Neuropilin-1 (a1 CUB Domain) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNeuropilin-1 (a1 CUB Domain)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot, Immunocytochemistry
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DescriptionThis antibody detects a 130 kDa* protein corresponding to the apparent molecular mass of neuropilin-1 on SDS-PAGE immunoblots of COS-7 cells transfected with mouse neuropilin-1. In immunocytochemistry, this antibody co-localizes with anti-HA in Cos-7 cells transfected with HA-tagged mouse neuropilin-1. Neuropilins are transmembrane proteins that contain two CUB domains (a1 and a2), two coagulation factor-like domains (b1 and b2), and a MAM domain in the extracellular region. These proteins have short cytoplasmic domains that include a PDZ-binding motif. The neuropilin (NRP) family includes NRP-1, NRP-2A, and NRP-2B. NRP-1 has been implicated as a receptor involved in axon guidance and VEGF signaling. NRP-1 mediates activation of intracellul
ImmunogenImmunogen: Neuropilin-1 synthetic peptide (coupled to carrier protein) corresponding to amino acids within the a1 CUB domain of human neuropilin-1. This sequence is highly conserved in rat and mouse neuropilin-1, and has low homology to neuropilin-2.
Other Names[NRP1; Vascular endothelial cell growth factor 165 receptor], [NRP1; NRP1; NP1; NRP; BDCA4; CD304; VEGF165R; DKFZp781F1414; DKFZp686A03134; NRP; VEGF165R]
Gene, Accession #Gene ID: 8829, NCBI: NP_003864.4, UniProt: O14786
Catalog #MBS472038
Price$385
Order / More InfoNeuropilin-1 (a1 CUB Domain) Antibody from MYBIOSOURCE INC.
Product Specific References• He, Z. & Tessier-Lavigne, M. (1997) Cell 90:739.• Nakamura, F. & Goshima, Y. (2002) Adv Exp Med Biol. 515:55.• Takahashi, T. et al. (1999) Cell 99:59.• Saban, M.R. et al. (2008) Am J Phys Renal Phys 295(1):F60 (ICC: H. Urothelium)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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