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Antigenic Specificity | Neuropilin-1 (a1 CUB Domain) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot, Immunocytochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects a 130 kDa* protein corresponding to the apparent molecular mass of neuropilin-1 on SDS-PAGE immunoblots of COS-7 cells transfected with mouse neuropilin-1. In immunocytochemistry, this antibody co-localizes with anti-HA in Cos-7 cells transfected with HA-tagged mouse neuropilin-1. Neuropilins are transmembrane proteins that contain two CUB domains (a1 and a2), two coagulation factor-like domains (b1 and b2), and a MAM domain in the extracellular region. These proteins have short cytoplasmic domains that include a PDZ-binding motif. The neuropilin (NRP) family includes NRP-1, NRP-2A, and NRP-2B. NRP-1 has been implicated as a receptor involved in axon guidance and VEGF signaling. NRP-1 mediates activation of intracellul |
Immunogen | Immunogen: Neuropilin-1 synthetic peptide (coupled to carrier protein) corresponding to amino acids within the a1 CUB domain of human neuropilin-1. This sequence is highly conserved in rat and mouse neuropilin-1, and has low homology to neuropilin-2. |
Other Names | [NRP1; Vascular endothelial cell growth factor 165 receptor], [NRP1; NRP1; NP1; NRP; BDCA4; CD304; VEGF165R; DKFZp781F1414; DKFZp686A03134; NRP; VEGF165R] |
Gene, Accession # | Gene ID: 8829, NCBI: NP_003864.4, UniProt: O14786 |
Catalog # | MBS472038 |
Price | $385 |
Order / More Info | Neuropilin-1 (a1 CUB Domain) Antibody from MYBIOSOURCE INC. |
Product Specific References | • He, Z. & Tessier-Lavigne, M. (1997) Cell 90:739.• Nakamura, F. & Goshima, Y. (2002) Adv Exp Med Biol. 515:55.• Takahashi, T. et al. (1999) Cell 99:59.• Saban, M.R. et al. (2008) Am J Phys Renal Phys 295(1):F60 (ICC: H. Urothelium) |