SPTAN1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SPTAN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: SPTAN1 antibody detects endogenous levels of total SPTAN1. Function: Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.Subunit Structure: Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts (via C-terminal spectrin repeats) with TRPC4. Interacts with CALM and EMD. Interacts with isoform 1 of ACP1. Identified in a complex with ACTN4, CASK, IQGAP1, MAGI2, NPHS1 and SPTBN1. Interacts with SHANK3 (via ANK repeats).Post-translational Modifications: Phosphorylation of Tyr-1176 decreases sensitivity |
| Immunogen | Immunogen: A synthesized peptide derived from human SPTAN1 Subcellular Location: Cytoplasm > Cytoskeleton. Cytoplasm > Cell Cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. Predicted Cross Reactivity: Bovine, Horse, Rabbit, Dog, Chicken Similarity: Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (91%) |
| Other Names | [(ALPHA)II-SPECTRIN; Alpha II Spectrin; Alpha-II spectrin; brain; EIEE5; FLJ17738; FLJ44613; Fodrin alpha chain; Fodrin, alpha; NEAS; Non erythrocytic spectrin alpha; non-erythroid alpha chain; SPECA; Spectrin alpha chain; Spectrin alpha chain brain; Spectrin alpha non erythrocytic 1; Spectrin; Spectrin non erythroid alpha chain; Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin); Spectrin, nonerythroid, alpha subunit; Spna2; SPTA 2; SPTA2; SPTA2_HUMAN; SPTAN 1; SPTAN1] |
| Gene, Accession # | [SPTAN1], Gene ID: 6709, NCBI: NP_001123910.1, UniProt: Q13813 |
| Catalog # | MBS9608394 |
| Price | $240, $280 |
| Order / More Info | SPTAN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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