MAGED1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAGED1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionMAGE-D1, also known as NRAGE or Dlxin-1, is a member of the MAGE family of proteins. Identified as a p75 neurotrophin receptor intracellular binding protein, MAGE-D1 induces developmental apoptosis of motoneurons, and is required for p75NTR-dependent apoptosis in sympathetic neurons. It is suggested that MAGE-D1 can suppress the motility and adhesion response of tumor cells. By forming a hetercomplex with Dlx/Msx family homeodomain proteins and Necdin, MAGE-D1 modulates the function of Dlx/Msx homeodomain during terminal differentiation and maturation of neurons. MAGE-D1 is also involved in the phosphorylation of IKK-alpha/beta, and subsequent transcriptional activation of the p65 subunit of NF-kappaB, via the XIAP-Tak1-Tab1 complex. (20100
ImmunogenImmunogen: Recombinant Protein
Other Names[MAGED1; DLXIN-1; NRAGE], [MAGED1; MAGED1; NRAGE; DLXIN-1; NRAGE]
Gene, Accession #[MAGED1], Gene ID: 9500, NCBI: Q9Y5V3.3, UniProt: Q9Y5V3
Catalog #MBS127359
Price$200, $275, $430
Order / More InfoMAGED1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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