CAD (Center), 780-809 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CAD (Center), 780-809 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.29 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD. The de novo synthesis of pyrimidine nucleotides isrequired for mammalian cells to proliferate. This gene encodes atrifunctional protein which is associated with the enzymaticactivities of the first 3 enzymes in the 6-step pathway ofpyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II),aspartate transcarbamoylase, and dihydroorotase. This protein isregulated by the mitogen-activated protein kinase (MAPK) cascade,which indicates a direct link between activation of the MAPKcascade and de novo biosynthesis of pyrimidine nucleotides. |
| Immunogen | n/a |
| Other Names | [CAD protein; Glutamine-dependent carbamoyl-phosphate synthase; Aspartate carbamoyltransferase; Dihydroorotase; CAD] |
| Gene, Accession # | [CAD], Gene ID: 790, NCBI: NP_004332.2, UniProt: P27708 |
| Catalog # | MBS9209870 |
| Price | $165, $370 |
| Order / More Info | CAD (Center), 780-809 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Ahuja, V., et al. J. Inherit. Metab. Dis. 31(4):481-491(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Olsen, J.V., et al. Cell 127(3):635-648(2006) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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