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Antigenic Specificity | Insulin receptor beta |
Clone | [C18C4] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, bovine, hamster, porcine, rabbit, sheep |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human, mouse, rat, bovine, hamster, pig, sheep and rabbit Insulin Receptor beta. Detects a band of ~98kDa by Western blot. The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes. |
Immunogen | Immunogen: Recombinant cytoplasmic domain of human Insulin Receptor beta. |
Other Names | [Insulin receptor; Insulin receptor; insulin receptor; insulin receptor; CD_antigen: CD220], [INSR; INSR; HHF5; CD220; IR] |
Gene, Accession # | [INSR], Gene ID: 3643, NCBI: P06213.4, UniProt: P06213 |
Catalog # | MBS565100 |
Price | $390 |
Order / More Info | Insulin receptor beta Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |