Insulin receptor beta Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityInsulin receptor beta
Clone[C18C4]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, bovine, hamster, porcine, rabbit, sheep
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRecognizes human, mouse, rat, bovine, hamster, pig, sheep and rabbit Insulin Receptor beta. Detects a band of ~98kDa by Western blot. The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.
ImmunogenImmunogen: Recombinant cytoplasmic domain of human Insulin Receptor beta.
Other Names[Insulin receptor; Insulin receptor; insulin receptor; insulin receptor; CD_antigen: CD220], [INSR; INSR; HHF5; CD220; IR]
Gene, Accession #[INSR], Gene ID: 3643, NCBI: P06213.4, UniProt: P06213
Catalog #MBS565100
Price$390
Order / More InfoInsulin receptor beta Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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