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Antigenic Specificity | MALT-1 (Paracaspase) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma. Human MALT1has two isoforms, isoform a is an amino acid protein of 824 amino acids, and human MALT1 isoform b is an amino acid protein of 813 amino acids. MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB. MALT1 is thought to play an important role in NF-kappaB signaling by enchancing NF-kappaB activation through interaction with Bcl10. Interaction between MALT1 and Bcl10 mediates IKK activation in vitro through facilitatii |
Immunogen | Immunogen Information: A recombinant protein fragment of human MALT1/Paracaspase was used as immunogen for this antibody |
Other Names | [MALT1; MLT; MALT lymphoma-associated translocation; Paracaspase; to MALT-1 (Paracaspase); MALT-1 (Paracaspase); MALT-1 (Paracaspase)], [MALT1; MALT1; MLT; MLT1; IMD12; PCASP1; MLT] |
Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: Q9UDY8.1, UniProt: Q9UDY8 |
Catalog # | MBS668709 |
Price | $270 |
Order / More Info | MALT-1 (Paracaspase) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |