Edit |   |
---|---|
Antigenic Specificity | IL-22 Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor. |
Other Names | [IL22R] |
Gene, Accession # | [IL-22], Gene ID: 58985, NCBI: AF286095 |
Catalog # | MBS9407745 |
Price | $320 |
Order / More Info | IL-22 Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |