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Antigenic Specificity | Cyclin-L1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Cyclin-L1 protein. Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152.Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S??sse, Nucleic Acids Res., Feb 2004; 32: 669 - 680. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human Cyclin-L1. |
Other Names | [Cyclin-L; CCNL1] |
Gene, Accession # | Gene ID: 57018, NCBI: NP_064703.1, UniProt: Q9UK58 |
Catalog # | MBS9405979 |
Price | $200, $255 |
Order / More Info | Cyclin-L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |