PDGFRB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPDGFRB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionPlatelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRalpha) and PDGF receptor beta (PDGFRbeta). PDGFRalpha and PDGFRbeta share 75% to 85% sequence homology between their two intracellular kinase domains, while the kinase insert and carboxy-terminal tail regions display a lower level (27% to 28%) of homology (1). PDGFRalpha homodimers bind all PDGF isoforms except those containing PDGF D. PDGFRbeta homodimers bind PDGF BB and DD isoforms, as well as the PDGF AB heterodimer. The heteromeric PDGF receptor alpha/beta binds PDGF B, C, an
ImmunogenImmunogen: Recombinant Protein
Other Names[CD140B; JTK12; PDGF-R-beta; PDGFR; PDGFR1], [PDGFRB; PDGFRB; IMF1; IBGC4; JTK12; PDGFR; CD140B; PDGFR1; PDGFR-1; PDGFR; PDGFR1; PDGF-R-beta; PDGFR-beta; PDGFR-1]
Gene, Accession #[PDGFRB], Gene ID: 5159, NCBI: P09619.1, UniProt: P09619
Catalog #MBS127836
Price$200, $275, $430
Order / More InfoPDGFRB Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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