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Antigenic Specificity | MATK |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. |
Immunogen | Immunogen: Purified recombinant fragment of human MATK expressed in E. Coli. |
Other Names | [CHK; CTK], [MATK; MATK; CHK; CTK; HYL; Lsk; HYLTK; HHYLTK; CTK; HYL; CHK] |
Gene, Accession # | [MATK], Gene ID: 4145, NCBI: NP_002369.2, UniProt: P42679 |
Catalog # | MBS850070 |
Price | $280 |
Order / More Info | MATK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |