Edit |   |
---|---|
Antigenic Specificity | Bad (Phospho Ser112) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Bad (S112) Polyclonal Antibody detects endogenous levels of Bad protein only when phosphorylated at S112. BCL2 associated agonist of cell death encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of BCL2 associated agonist of cell death. Alternative splicing of BA |
Immunogen | Immunogen: Synthesized peptide derived from human Bad around the phosphorylation site of S112 |
Other Names | [Rabbit Bad (phospho Ser112); BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter] |
Gene, Accession # | [BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
Catalog # | MBS9701033 |
Price | $130, $220, $325 |
Order / More Info | Bad (Phospho Ser112) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |