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Antigenic Specificity | IEX-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IEX-1 is a stress inducible gene that is induced by ionizing radiation, ultraviolet radiation, and a variety of growth factors, i.e., FAS and TNF-a. IEX-1 is widely expressed in epithelial and endocrine tissues, as well as in vascular endothelium. It plays an important role in the regulation of cellular growth, cell death and oncogenesis. IEX-1 is precisely regulated by multiple transcription factors such as p53, NF-kB/rel, Sp1 and c-Myc, to ensure rapid and transient expression of IEX-1 in cells under a variety of stress conditions. IEX-1 is expressed as both a longer form (IEX1L) and a splice variant, designated IEX1S. It is localized to the nucleus and perinuclear region. Overexpression of IEX-1 facilitates apoptosis and cell cycle progr |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 24 amino acid peptide near the center of human IEX1. |
Other Names | [Immediate early response 3, IER3, DIF2, PRG1, GLY96] |
Gene, Accession # | [IEX-1], Gene ID: 8870, NCBI: NP_003888.2, UniProt: P46695 |
Catalog # | MBS9401055 |
Price | $320 |
Order / More Info | IEX-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |