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Antigenic Specificity | NEFM |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 2.22 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human NEFM (NP 005373.2). Immunogen Sequence: EAAIRALRKDIEEASLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLT |
Other Names | [NEFM; NEF3; NF-M; NFM; neurofilament medium] |
Gene, Accession # | [NEFM], Gene ID: 4741, NCBI: NP_005373.2, UniProt: P07197 |
Catalog # | MBS9140829 |
Price | $260 |
Order / More Info | NEFM Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |