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Antigenic Specificity | TPR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for TPR detection. Tested with WB in Human; Mouse; Rat.Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human TPR (MLQAEKKLLEEDVKRWKARNQHLVSQQKD). |
Other Names | [Nucleoprotein TPR; Megator; NPC-associated intranuclear protein; Translocated promoter region protein; TPR; Translocated promoter region, nuclear basket protein] |
Gene, Accession # | [TPR], Gene ID: 7175, NCBI: NP_003283.2, UniProt: P12270 |
Catalog # | MBS1751267 |
Price | $315 |
Order / More Info | TPR Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Gonzatti-Haces, M., Seth, A., Park, M., Copeland, T., Oroszlan, S., Vande Woude, G. F. Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases. Proc. Nat. Acad. Sci. 85: 21-25, 1988. 2. Miranda, C., Minoletti, F., Greco, A., Sozzi, G., Pierotti, M. A. Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization. Genomics 23: 714-715, 1994. |