TPR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTPR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for TPR detection. Tested with WB in Human; Mouse; Rat.Background: The tetratricopeptide repeat (TPR) is a structural motif. This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence of human TPR (MLQAEKKLLEEDVKRWKARNQHLVSQQKD).
Other Names[Nucleoprotein TPR; Megator; NPC-associated intranuclear protein; Translocated promoter region protein; TPR; Translocated promoter region, nuclear basket protein]
Gene, Accession #[TPR], Gene ID: 7175, NCBI: NP_003283.2, UniProt: P12270
Catalog #MBS1751267
Price$315
Order / More InfoTPR Antibody from MYBIOSOURCE INC.
Product Specific References1. Gonzatti-Haces, M., Seth, A., Park, M., Copeland, T., Oroszlan, S., Vande Woude, G. F. Characterization of the TPR-MET oncogene p65 and the MET protooncogene p140 protein-tyrosine kinases. Proc. Nat. Acad. Sci. 85: 21-25, 1988. 2. Miranda, C., Minoletti, F., Greco, A., Sozzi, G., Pierotti, M. A. Refined localization of the human TPR gene to chromosome 1q25 by in situ hybridization. Genomics 23: 714-715, 1994.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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